Click name to see page Return to Biological Sciences Biosciences Faculty Armbruster, Jonathan Barbaree, James Best, Troy L. Bowling, Scott A. Boyd, Robert Bradley, James T. Brown, Alfred Chadwick, Nanette E. Cobine, Paul Dobson, F. Stephen Dute, Roland Feminella, Jack W. Fielman, Kevin Folkerts, Debbie R. Folkerts, George W. Goertzen, Leslie Guyer, Craig Halanych, Ken Henry, Raymond P. Hill, Geoffrey E. Hood, Wendy R. Jacobsen, Shawn Kearley, Matthew Kempf, Stephen C. Liles, Mark R. Lishak, Robert S. Locy, Bob McVay, Catherine Mendonca, Mary T. Miller, Michael E. Moss, Anthony G. Person, Davonya Rashotte, Aaron Roberts, Sharon Santos, Scott R. Silo-Suh, Laura Singh, Narendra Suh, Sang-Jin Sundermann, Christine A. Wit, Lawrence C. Wooten, Marie W. Wooten, Michael C. Wysocka-Diller, Joanna

Mark Liles Ph.D., Assistant Professor

Office Location:  316 Rouse Life Science Bldg 216 Rouse Life Science Bldg (lab) Mailing Address: Department of Biological Sciences 101 Rouse Life Science Bldg Auburn University, AL 36849 Tel: (334) 844-1656 Fax: (334) 844-1645 lilesma@auburn.edu   Laboratory Web Page

Education & Employment
2005-present, Auburn University, Assistant Professor
1998-2005 University of Wisconsin-Madison, NIH Postdoctoral Fellow
1992-1998 Northwestern University, Ph. D. Microbiology, NIH Predoctoral Research Fellow
1991-1992 Touro Infirmary, New Orleans, Research Technician
1987-1991 Tulane University, New Orleans, B.S. in Biology
 

Research & Teaching Interests
Environmental microbiology. Community genomics of microbial assemblages, with an emphasis on antibiotic biosynthetic pathways and mobile genetic elements that can confer antibiotic resistance. Also, the use of bacteriophage therapy to prevent bacterial disease in aquaculture production.

Recent Publications
George, Isabelle, Liles, Mark R., Hartmann, Manuela, Ludwig, Wolfgang, Goodman, Robert M.,and Agathos, Spiros N. Changes in soil Acidobacteria communities after 2,4,6-trinitrotoluene contamination,
submitted.

Sabree, Z.L., Bergendahl, V., Liles, M.R., Goodman, R.M., Handelsman, J., and Burgess, D. (2006) Identification and characterization of the Acidobacterium capsulatum major sigma factor. Gene, 376:144-151.

Liles, M.R., Williamson, L.L., Goodman, R.M., and Handelsman, J. (2004) Isolation of high molecular weight genomic DNA from soil bacteria for genomic library construction. In: Molecular Methods in Environmental Microbiology, Kowalchuk, G.A.; de Bruijn, F.J.; Head, I.M.; Akkermans, A.D.; van Elsas, J.D. (Eds.), pp. 839-852.

Liles, M.R., Manske, B.F., Bintrim, S.B., Handelsman, J., and Goodman, R.M. (2003). A census of rRNA genes and linked genomic sequences within a soil metagenomic library. Applied and Environmental Microbiology, 69 (5):2684-2691.

Handelsman, J., Liles, M.R., Mann, D., Riesenfeld, C., and Goodman, R.M. (2002) Cloning the metagenome: Culture-independent access to the diversity and functions of the uncultivated microbial world. Methods in Microbiology, 33:241-255.

Gillespie, D.E., Brady, S.F., Bettermann, A.D., Cianciotto, N.P., Liles, M.R., Rondon, M.R., Clardy, J., Goodman, R.M., Handelsman, J. (2002). Isolation of antibiotics turbomycin A and B from a metagenomic library of soil microbial DNA. Applied and Environmental Microbiology, 68:4301-4306.

Nelson, B.P.,* Liles, M.R.,* Frederick, K.B., Corn, R.M., and Goodman, R.M. (2002) Label-free detection of 16S ribosomal RNA hybridization onto reusable DNA arrays using SPRi. Environmental Microbiology, 4(11):735-743.

Rondon, M.R., August, P.R., Bettermann, A.D., Brady, S.F., Grossman, T.H., Liles, M.R., Loiacono, K.A., Lynch, B.A., MacNeil, I.A., Minor, C., Tiong, C.L., Gilman, M., Osbourne, M.S., Clardy, J., Handelsman, J., and Goodman, R.M. (2000) Cloning the soil metagenome: A strategy for accessing the genetic and functional diversity of uncultured microorganisms. Applied and Environmental Microbiology, 66 (6): 2541-2547.

Liles, M. R., Scheel, T. A., and Cianciotto, N. P. (2000). Discovery of a non-classical siderophore, legiobactin, produced by strains of Legionella pneumophila. Journal of Bacteriology, 182 (3): 749-757.

Liles, M. R., Edelstein, P. H., and Cianciotto, N. P. (1999). The prepilin peptidase is required for protein secretion by and the virulence of the intra-cellular pathogen Legionella pneumophila. Molecular Microbiology, 31(3):959-970.

Liles, M. R., Viswanathan, V. K., and Cianciotto, N. P. (1998) Identification and temperature regulation of Legionella pneumophila genes involved in type IV pilus biogenesis and type II secretion. Infection and Immunity, 66:1776-1782.

Courses: