X-Ray Diffraction Facility

X-Ray Diffraction Facility


The department houses the University X-Ray Diffraction Facility that contains a state-of-the-art Bruker APEX single crystal X-ray diffractometer with an area detector and an Oxford cryostream low-temperature device. Using this instrument, faculty and trained graduate students are capable of performing single-crystal X-ray structural determinations. This instrument is an important tool for our inorganic and organic faculty involved in complex syntheses.  The facility also houses a new Rigaku powder X-ray diffractometer.  

Bruker D8 Venture Single Crystal X-ray Diffractometer for biological and chemical crystallography

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Rigaku SmartLab Powder X-ray Diffractometer

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Single Crystal X-Ray Diffraction

  • Small molecules; Absolute configuration
  • Macromolecules (proteins; protein-ligand complexes)
  • Bruker D8 Venture with Incoatec DIAMOND 3.0 X-ray micro-source
  • Dual source X-rays: Cu Kα and Mo Kα
  • Photon II CPAD detector with shutter less data acquisition
  • Oxford 800 series cryostream low-temperature device capable of data collections 100 – 300 K.


Dr. P. Raj Pokkuluri (XRD Facility Director)

Dr. Pokkuluri has extensive experience with protein crystallization, structure determination and analysis of protein structures.

Dr. Pokkuluri is available to help researchers carry out crystallization experiments (both small and macromolecules), and aid the downstream workflow to add/enhance the structural biology component of research on your protein of interest.

Powder/Thin-Film X-Ray Diffraction

  • Rigaku SmartLab (installed March 2021)
  • Temperature range: 15°C - 1000°C possible


Dr. Byron Farnum (Chemistry & Biochemistry)
Dr. Ryan Comes (Physics)



Use of the X-ray center has a nominal fee. Contact XRD Facility Director Dr. Raj Pokkuluri for more information.