PDA

Spring Semester, 2004
Class Location: Tues. and Thurs. - 134 Chemistry, Wed. and Fri. - 2370 Haley
Scheduled Hours: MTWH, 11:00-11:50

Course Instructors: Dr. Charles Breese (Office: 408 Pharmacy)
Dr. Maynard Hamrick (Office: 403 Pharmacy Building)
Dr. Tom Riley, Course Coordinator (Office: 306 Pharmacy Building)
Dr. Jack DeRuiter (Office: 304 Pharmacy)
Dr. Forest Smith (Office: 308 Pharmacy)

Course Description
Course Outline and Lecture Schedule
Course Examinations and Policies
Course Information Resources
Remedial Materials
Study Guides and Assignments
Query Form

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  • Course Description:

    • The objective of PYPS5120 is to present, in an integrated manner chemical and pharmacological principles of drug action. In addition, descriptions of the medicinal chemistry and pharmacology of drugs affecting cholinergic, adrenergic and dopaminergic neurotransmission will be provided.

  • Course Outline and Lecture Schedule

    • A. Physicochemical Principles of Drug Action [Dr. DeRuiter]

    B. Chemical and Pharmacological Aspects of Drug Disposition [Dr. Riley]

    C. Target Sites of Drug Action – Introductory Concepts [Dr. Hamrick]

    D. Cholinergic Agents [Drs. Breese and F. Smith]

    E. Adrenergic Agents [Drs. Smith and Breese]
    F. Dopaminergic Agents [Drs. Breese and Smith]

  • Course Examinations and Policies

    • DAY EXAM PERCENT POINTS GRADE
    TBA Dr. DeRuiter 20 89.6-100 A
    TBA Dr. Riley 20 79.6-89.5 B
    TBA Drs. Hamrick
    Breese
    Smith         		30 69.6-79.5 C
    TBA Final Exam
    Drs. Breese
    Smith         		30 60-69.5 D
    * * * less than 60.0
    		 F

    A. Students are expected to attend all scheduled lectures.

    B. Students are expected to carry out all assigned work and to take all examinations at the scheduled times. It is the responsibility of the student to advise the instructor in advance of any anticipated absence from an examination. No student will be allowed to take an exam prior to its scheduled date and time. Make-up exams will not normally be provided. Make-up exams, if given, will be scheduled at the discretion of the instructor.

    C. Students will adhere to the School of Pharmacy Honor Code in completing all requirements of the course.

    D. Questions concerning course content should be directed to the instructor responsible for that content. Questions concerning course policy and/or procedures should be directed to the Course Coordinator (Dr. Riley).


    Here are some ready-made excuses for missing exams that I've heard recently!
    So, don't use these - they're already taken.     Smile!!!

  • Course Information Resources


    • DR. RILEY'S SLIDES:

    ADME LINKS:

    (1) Primer on Solubility of Organic Medicinal Agents (OMAs)
    (2) Estimating the Solubility of an OMA
    (3) Chemistry of Drug Biodisposition - Glossary of Terms
    (4) A First Course in Pharmacokinetics and Biopharmaceutics
    (5) General Principles: Pharmacokinetics
    (6) Principles of Pharmacology
    (7) Review of Drug Metabolism


    Online Remedial Material

  • The Comic Book Periodic Table of Elements
  • Primer on Acid-Base Properties of OMAs
  • List of Acidic and Basic Drugs
  • Organic Chemistry Tutorials
  • Concepts of Biochemistry
  • Chemistry Reviews OnLine
  • Primer on Solubility of Organic Medicinal Agents (OMAs)
  • Estimating the Solubility of an OMA
  • Review of Chemical Neurotransmission
  • A First Course in Pharmacokinetics and Biopharmaceutics
  • Cytochrome p450 Drug Metabolism and Interactions
  • Review of Drug Disposition


    • Click here to go tothe Pharmacy Intranet