Raymond P. Henry, Ph.D.

Professor, Assistant Chair

Comparative Physiology and Biochemistry
OFFICE: 324 Rouse Life Sciences Building
PHONE: 334-844-9264
E-MAIL: henryrp@auburn.edu

Honors/Awards:

Current National Science Foundation Support: Salinity-sensitive induction of transport enzymes for euryhaline invertebrates
Alabama Agriculture Experiment Station Outstanding Research Award (1989)
Alumni Professor (1996-2001)
Dean's Research Award (1998)
Invited speaker to 10 national and international symposia (1984 - present)
Organizer of four nationa/international symposia (1984 - present)

Research/Interests

1. Environmental signal transduction: This area focuses on how an environmental signal can result in selective gene activation, using salinity-mediated induction of carbonic anhydrase expression in the gills of euryhaline organisms as a model experimental system.

2. Environmental toxicology: We have recently initiated a study on the effects of heavy metals on carbonic anhydrase activity, the enzyme's physiological role in ion transport and regulation, and its expression in euryhaline crustaceans.

3. Bimodal breathing: This is an ongoing project studying the transition from gill to lung breathing in amphibious crustaceans, the mechanisms of respiratory gas exchange and acid-base balance in water and air, and the control of ventilation.

Completed Theses/Dissertations:

Sheryl Prassack (1995) M.S. Thesis. Bimodal breathing and overwintering strategies of two species of freshwater turtles.

Brian P. Bagatto (1995) M.S. Thesis. Bimodal breathing and recovery from exhaustive exercise in two species of freshwater turtles.

Christian A. Combs (1992) M.S. Thesis. Salinity and metabolic adaptations in three taxa of the stone crab, Menippe, in the Gulf of Mexico.

Paul A. Stone (1990) M.S. Thesis. Cutaneous surface area and bimodal breathing in three species of freshwater turtles.

Theses/Dissertations in progress:

Kristen Lenertz (2000) M.S. Thesis. Effects of parasitism on grazing, metabolic physiology, and reproductive potential in the freshwater snail Elimia flava. (co-advisor with J.W. Feminella).

Anne Estes (2000) M.S. Thesis. Carbonic anhydrase distribution and induction in the symbiotic jellyfish, Cassiopea xamanchana. (co-advisor with S.C. Kempf).

Selected Publications:

Research Articles

Serrano L. Halanych KM. Henry RP. 2007 Salinity-stimulated changes in expression and activity of two carbonic anhydrase isoforms in the blue crab Callinectes sapidus. Journal of Experimental Biology 210:2320-32

Roy LA. Davis DA. Saoud IP. Henry RP. 2007 Branchial carbonic anhydrase activity and ninhydrin positive substances in the Pacific white shrimp, Litopenaeus vannamei, acclimated to low and high salinities. Comparative Biochemistry & Physiology 147A:404-11

Henry RP. Thomason KL. Towle DW. 2006. Quantitative changes in branchial carbonic anhydrase activity and expression in the euryhaline green crab, Carcinus maenas, in response to low salinity exposure. Journal of Experimental Zoology 305A:842-50

Henry RP. Campoverde M. 2006. Neuroendocrine regulation of carbonic anhydrase expression in the gills of the euryhaline green crab, Carcinus maenas. Journal of Experimental Zoology 305A:663-8

Henry RP. 2006. Functional evidence for the presence of a carbonic anhydrase repressor in the eyestalk of the euryhaline green crab Carcinus maenas. Journal of Experimental Biology 209:2595-2605

Henry RP. Borst DW. 2006. Effects of eyestalk ablation on carbonic anhydrase activity in the euryhaline blue crab Callinectes sapidus: neuroendocrine control of enzyme expression. Journal of Experimental Zoology 305A:23-31

Bagatto, B.P., and R.P. Henry (1999) Exercise and forced submergence in the pond slider (Trachemys scripta) and softshell turtle (Apalone ferox): influence on bimodal gas exchange, diving behavior, and blood acid-base status. J. Exp. Biol. 202:267-278.

Henry, R.P., Y. Wang, and C.M. Wood (1997) Carbonic anhydrase facilitates CO2 and NH3 transport across the sarcolemma of trout white muscle. Amer. J. Physiol. 272:R1754-R1761.

Morgan, I.P., R.P. Henry, and C.M. Wood (1997) The mechanism of acute silver toxicity in freshwater rainbow trout (Oncorhynchus mykiss) is inhibition of gill Na+ and Cl- transport. Aquatic Toxicology 38:145-163.

Henry, R.P., and P.J. Walsh (1997) Mitochondrial citrulline synthesis in the ureagenic toadfish, Opsanus beta, is dependent on carbonic anhydrase activity and glutamine transport. J. Exp. Zool. 279:521-529.

Henry, R.P., S.A. Jackson, and C.P. Mangum (1996) Ultrastructure and transport-related enzymes of the gills and coxal gland of the horseshoe crab, Limulus polyphemus. Biol. Bull. 191:241-250.

Watts, S.A., W.E. Yeh, and R.P. Henry (1996) Hypoosmotic stimulation of ornithine decarboxylase activity in the brine shrimp, Artemia franciscana. J. Exp. Zool. 274:15-22.

Piller, S.C., R.P. Henry, J.E. Doeller, and D.W. Kraus (1995) A comparison of the gill physiology of two euryhaline crab species, Callinectes sapidus and C. similis. I. Energy production, transport-related enzymes and osmoregulation as a function of acclimation salinity. J. Exp. Biol. 198:349-358.

Invited Reviews/Book Chapters

Henry, R.P. (1994) Morphological, physiological, and behavioral characterization of bimodal breathing crustaceans. Amer. Zool. 34:205-215.

Henry, R.P. (1995) Nitrogen metabolism and excretion for cell volume regulation in invertebrates. In: Nitrogen Metabolism and Excretion (P.J. Walsh and P.A. Wright, eds.) CRC Press, Boca Raton, FL. Pp 63-73.

Henry, R.P. (1996) Multiple roles of carbonic anhydrase in cellular transport and metabolism. Ann. Rev. Physiol. 58:523-538.

Henry, R.P., and T.A. Heming (1998) Carbonic anhydrase and respiratory gas exchange. In: Fish Physiology, vol. 17 (S.F. Perry and B.L. Tufts, eds.) Academic Press, New York. Pp. 75-111.