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Biographical Sketch

PERSONAL

• Born: December 2, 1939; Mishawaka, IN
• Married: Phyllis W. (1960)
• Children: Thomas N., Jr. (1962) and Mark S. (1964)
• Home Address: 902 Boddie Lane, Auburn, AL 36830

PRESENT POSITION

• Professor of Medicinal Chemistry
• Department of Pharmacal Sciences
• School of Pharmacy
• Auburn University
• Auburn University, AL 36849-5503
• Voice: (334)844-8320; FAX: (334)844-8331

EDUCATION

• Owensboro Catholic High School, Owensboro, KY, 1957
• Brescia College, Owensboro, KY, 1957-1960 (pre-professsional)
• University of Kentucky, Lexington, KY, 1960-1963 (B.S. Pharmacy)
• University of Minnesota, Minneapolis, MN, 1963-1969 (Ph.D. Medicinal Chemistry/Organic Chemistry/Biochemistry)

PROFESSIONAL EXPERIENCE

• Assistant Professor, 1969-1972, Dept. Medicinal Chemistry, School of Pharmacy, University pf Mississippi, University, MS.
• Associate Professor, 1972-1979, Dept. Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, MS.
• Professor, 1979-1982, Dept. Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, MS.
• Professor and Head, 1982-1990, Dept. Pharmacal Sciences, School of Pharmacy, Auburn University, Auburn, AL.
• Interim Dean, 1987-1988, School of Pharmacy, Auburn University, Auburn, AL.
• Professor, 1990-Present, Division of Medicinal Chemistry, School of Pharmacy, Auburn University, Auburn, AL.
• Interim Dean, 1992-1994, School of Pharmacy, Auburn University, Auburn, AL.

INSTRUCTION

• Principles of Medicinal Chemistry (professional and graduate)
• Medicinal Chemistry of Therapeutic Agents (professional and graduate)
• Stereochemical Aspects of Drug Action (graduate)
• Recent Advances in Drug Therapy (continuing education)

RESEARCH

• Design and Synthesis of Novel Ligands for Various Receptor Systems
• Stereochemistry as a Probe of Molecular Drug Receptor Structure
• Stereochemical Aspects of Drug Action
• Stereo-Structure-Activity-Relationships

PUBLICATIONS

• Research publications in J. Med. Chem., J. Heterocycl Chem., J. Pharm. Sci.
• Professional publications in U. S. Pharmacist
• "Isomerism," Chapter In Encyclopedia of Pharmaceutical Technology, Marcel Dekker, Inc., New York, 1993.
• "Stereoisomerism in Pharmaceuticals: New Directions in Drug Discovery and Development," Technomic Publishing Company, Lancaster, PA, 1990.
• "Antianginal Agents," Chapter in "Handbook of Medicinal Chemistry," M. Verderame, Ed., C. R. C. Press, Inc., Boca Raton, FL, 1986.
• "Prodrugs - Rationale and Therapeutic Utility," Lederle Laboratories, Pearl River, NY, 1982.
• "A Pocket Guide to Organic Medicinal Structures," Taylor Publications, Camden, ME 1979.
• "Conformationally-Restricted Histamine H2-Receptor Antagonists Containing a Tropane Ring," U. S. Patent Number 4,432,983, 1982.
• "1-(2-Phenylethyl)-3-methyl-4-(N-propananilido)piperidine As a Narcotic Analgetic Compound," U. S. Patent Number 3,923,992, December 2, 1975.

ASSOCIATIONS AND CONSULTING

• American Chemical Society, Alabama and Mississippi Academies of Sciences, Alabama Pharmacy Association, Alabama Commission on Pharmacy, American Heart Association, Phi Delta Chi.
• NIH Special Study Section, SBIR Program, Washington, DC.
• NIH/NINCDS Site Visit Team
• American Council on Pharmaceutical Education, Evaluation Team Member
• Rives & Peterson Law Offices, Attorneys At Law, Birmingham, AL
• D. H. Todd, Attorney at Law, Columbus, GA
• Lyons, Pipes & Cook, Attorneys At Law, Mobile, AL
• Manuscript and Book Reviewer: Journal of Medicinal Chemistry, American Journal of Pharmaceutical Education, Bioorganic & Medicinal Chemistry Letters, Journal of Heterocyclic Chemistry.
• Seminar Coordinator, Technomic Publishing Company, Inc.
• Contributing Editor, U. S. Pharmacist
• Associate Editor, Journal of Pharmacy Teaching
• Prodrugs in Drug Development, Lederle Laboratory, Pearl River, NY

HONORS

• Elected to membership, Phi Lambda Sigma, Rho Chi and The Society of the Sigma XI
• Outstanding Teacher Award, School of Pharmacy, University of Mississippi
• Public Health Service Predoctoral Trainee, Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota

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