[A] Journal publications:
- Mathews ST, Rakhade S, Zhou X, Parker G, Coscina DV, Grunberger G. Fetuin-null mice are protected against obesity and insulin resistance associated with aging. Biochemical and Biophysical Research Communications 350:437-443, 2006 [PUBMED]
- Leff T, Mathews ST, Camp HS. PPARg, the adipocyte and diabetes. Experimental Diabesity Research 5:99-109, 2004 [PUBMED]
- Chu, AJ, Mathews ST. Poly-L-hisditine downregulates fibrinolysis. Blood Coagulation and Fibrinolysis 14:627-632, 2003 [PUBMED]
- Chu AJ, Mathews ST. Anticoagulant potential of an antibody against factor VII. Journal of Surgical Research 114:37-41, 2003 [PUBMED]
- Chu AJ, Rauci, M, Nwobi OI, Mathews ST, Beydoun S. Novel anticoagulant activity of polyamino acid offsets bacterial endotoxin-induced extrinsic hypercoagulation: Downregulation of monocytic tissue factor-dependent FVII activation. Journal of Cardiovascular Pharmacology 42:477-483, 2003 [PUBMED]
- Chu AJ, Beydoun S, Mathews ST, Hoang J. Novel anticoagulant polyethylenamine suppresses blood coagulation: Inhibition of thrombin-catalyzed fibrin formation. Archives of Biochemistry and Biophysics 415:101-108, 2003 [PUBMED]
- Hegele RA, Cao H, Frankowski C, Mathews ST, Leff T: PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy. Diabetes 51:3586-3590, 2002 [PUBMED]
- Mathews ST, Singh GP, Ranaletta M, Cintron VJ, Qiang X, Goustin AS, Jen K-LC, Charron MJ, Jahnen-Dechent W, Grunberger G: Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene. Diabetes 51:2450-2458, 2002 [PUBMED]
- Chu AJ, Rauci M, Nwobi OI, Mathews ST, Beydoun S. Novel anticoagulant activity of polybrene: Inhibition of monocytic tissue factor hypercoagulation following bacterial endotoxin induction. Blood Coagulation and Fibrinolysis, 13: 123-128, 2002 [PUBMED]
- Mathews ST, Deutsch DD, Iyer G, Hora N, Pati B, Marsh J and Grunberger G. a2-HS glycoprotein kinetics after acute myocardial infarction: Development of a sandwich ELISA using commercial antibodies. Clinica Chimica Acta, 319:27-34, 2002 [PUBMED]
- Grunberger G, Qiang X, Li Z-G, Mathews ST, Sbriessa D, Shisheva A, Sima AAF: Molecular basis for the insulinomimetic effects of C-peptide. Diabetologia 44:1247-1257, 2001 [PUBMED]
- Mathews ST, Chellam N, Srinivas PR, Cintron V, Leon MA, Goustin AS, Grunberger G: a2-HSG, a specific and reversible inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. Molecular and Cellular Endocrinology 164(1-2): 87-98, 2000 [PUBMED]
- Mathews ST, Srinivas PR, Leon MA, Grunberger G: Bovine fetuin is an inhibitor of insulin receptor tyrosine kinase. Life Sciences 61(16): 1583-1592, 1997 [PUBMED]
- Srinivas PR, Deutsch DD, Mathews ST, Goustin AS, Leon MA, Grunberger G: Recombinant human a2-HS glycoprotein inhibits insulin-stimulated mitogenic pathway without affecting metabolic signaling in Chinese Hamster Ovary cells overexpressing the human insulin receptor. Cellular Signaling 8: 567-573, 1996 [PUBMED]
- Mathews ST, Selvam R: Changes in glutathione metabolic enzymes in erythrocytes of Plasmodium vivax-infected patients. Clinica Chimica Acta 219: 159-165, 1993 [PUBMED]
- Selvam R, Mathews ST: Biochemical alterations in vivax malaria following radical treatment. Indian Journal of Malariology 29: 103-111, 1992 [PUBMED]
- Mathews ST, Selvam R: Effect of radical treatment on erythrocyte lipid peroxidation in Plasmodium vivax-infected malaria patients. Biochemistry International 25: 211-220, 1991 [PUBMED]
- Mathews ST, Selvam R: Cholinesterase and acetylcholinesterase activities in patients infected with Plasmodium vivax. Medical Science Research 19: 807-809, 1991
- Mathews ST, Kumaresan PR, Selvam R: Glucose-6-phosphate dehydrogenase deficiency and malaria-a study on North Madras population. Journal of Communicable Diseases 23: 178-181, 1991 [PUBMED]
- Mathews ST, Latha VM, Satakopan VN, Srinivasan R: Effect of simulated water stress on IAA oxidase in groundnut (Arachis hypogea) seedlings. Current Science 57: 485-486, 1988
[B] Articles in Books:
- Davis J*, Kim T, Mathews ST. The Role of Curcumin in Insulin Action and Glucose Metabolism. In: Martirosyan, DM (Ed.): Functional Foods for Chronic Diseases: Cadiovascular Diseases, Diabetes, and Aging (In press), 2007
- Grunberger G, Mathews ST, Deutsch DD: Tyrosine Kinase Inhibitors. In: Grunberger G, Zick Y (Eds): Insulin Signaling: From Cultured Cells to Animal Models, Frontiers in Animal Diabetes Research, Taylor & Francis Inc., pp.281-297, 2002
- Josekutty PC, Mathews ST: Implications of Plant Breeders Rights for material propagated through in vitro methods. In: Breeders and Farmers Rights: An Interdisciplinary Dialogue, CRSARD, Madras, pp.213-220, 1994
- Mathews ST, Selvam R: Peroxidative and antiperoxidative agents in red blood cells in human malaria In: Kidwai AM, Upreti RK, Ray PK (eds) Biomembranes in Health and Disease, Vol II. Today and Tomorrow's Printers and Publishers, New Delhi, pp.545-560, 1991
[C] Patents:
- Mathews ST, Kim T, Papizan JB*. Methods and compositions for treating obesity and diabetes (USPTO 07-011, 2006, patent pending)
- Mathews ST, Grunberger G, Goustin AS, Srinivas PR. Inhibition of alpha2-HS glycoprotein (Ahsg/Fetuin) in obesity and insulin control of glucose homeostasis (PCT: WO 02/39923 A2)
[D] Published Abstracts:
- Papizan JB*, Kim T, Wernette C, White BD, Mathews ST: A novel role for leptin in regulating phosphorylation status of alpha2-HS glycoprotein, a physiological inhibitor of insulin action. Keystone Symposia, Diabetes: Molecular Genetics, Signaling Pathways and Integrated Physiology, Keystone, CO, Jan.14-19, 2007, #302/p.81, 2007
- Kim T, Price JC, Sunkara R, Mathews ST. Fetuin inhibits insulin-stimulated glucose uptake and glycogen synthesis in L6 GLUT4myc skeletal muscle cells. 66th Scientific Sessions, American Diabetes Association, Washington D.C., June 9-13, 2006. Diabetes (Suppl.1),A285, 2006
- White BD, Wernette CM, Mathews ST, Kim T, Judd R: Leptin-treated diabetic rats become hypoglycemic during a short-term fast and cannot derive glucose from lactate or alanine. Keystone Symposia, Jan.21-26, 2006, Vancouver, British Columbia, 2006
- Li G, Mathews ST, Leff T: Molecular analysis of a lipodystrophy associated point mutation (Arg425Cys) in the human PPARG gene. 64th Scientific Sessions, American Diabetes Association, Orlando, Florida, June 4-8, 2004. Diabetes 53 (Suppl.2), A276, 2004
- Mathews ST, Camp HS, Liyun D, Leff T: Modulation of insulin sensitivity by nutrition in mice expressing constitutively active PPARg1 in skeletal muscle. Keystone Symposia (Molecular Control of Adipogenesis and Obesity), Banff, Alberta, Canada, 2004
- Mathews ST, Hegele RA, Leff T: Molecular analysis of a human PPARg mutation associated with lipodystrophy and diabetes. The 18th International Diabetes Federation Congress, Paris, France, Diabetologia 46 (Suppl.2), A226, 2003
- Chu AJ Nwobi OT, Mathews ST: Polyamino acids antagonize monocytic tissue factor hypercoagulation in response to bacterial endotoxin. XIV World Congress of Pharmacology, San Francisco. The Pharmacologist 44 (Suppl.1), A12, 2002.
- Mathews ST, Rakhade S, Zhou X, Coscina DV, Grunberger G: Improved insulin sensitivity of fetuin-null mice protects aging-induced obesity and insulin resistance. 62nd Scientific Sessions, American Diabetes Association, San Francisco. Diabetes 51 (Suppl.2), A328, 2002
- Mathews ST, Cintron V, Qiang X, Singh GP, Jahnen-Dechent W, Goustin AS, Grunberger G: Enhanced glucose clearance and insulin sensitivity in fetuin-deficient mice. 2nd Annual International Motor City Diabetes Symposium, Detroit. J Diab.Compl. 15(1) pp.23, 2001
- Qiang X, Li Z-G, Mathews ST, Sima AAF, Grunberger G: Are C-peptide effects mediated by the insulin receptor? 61st Scientific Sessions of the American Diabetes Association, Philadelphia. Diabetes 50 (Suppl.2) A257, 2001
- Mathews ST, Ranalletta M, Charron MJ, Grunberger G: Increased phosphorylation of insulin receptor substrates and augmented glucose utilization in fetuin null mice. VII International Symposium on Insulin Receptors and Insulin Action, Geneva, May 5-9, 2001
- Qiang X, Srinivas PR, Mathews ST, Riedel H, Sima AAF, Grunberger G: C-peptide stimulates glycogen synthesis in L6 myoblasts. 2nd Annual International Motor City Diabetes Symposium, Detroit. J Diab.Compl. 15(1) pp.21, 2001
- Mathews ST, Singh GP, Ana LS, Buison EJ, Jen K-LC, Goustin AS, Grunberger G: Increased insulin sensitivity in mice lacking fetuin (Ahsg) gene. Oral presentation: 36th Annual Meeting of the European Association for the Study of Diabetes, Jerusalem. Diabetologia 43 (Suppl. 1): I-IV, A34, 2000
- Mathews ST, Singh GP, Qiang X, Goustin AS, Jahnen-Dechent W, Grunberger G: Mice Null for Ahsg suggest a new physiological role for fetuin in insulin control of glucose homeostasis. Oral presentation:60th Scientific Sessions of the American Diabetes Association, San Antonio. Diabetes 49 (Suppl.1) A6, 2000
- Grunberger G, Qiang X, Mathews ST, Li Z-G, Sima AAF, Sbrissa D, Shisheva A: C-peptide stimulates glycogen synthesis via a wortmannin-sensitive and Akt-independent pathway. 60th Scientific Sessions of the American Diabetes Association, San Antonio. Diabetes 49 (Suppl.1) A447, 2000
- Mathews ST, Srinivas PR, Grunberger G, Goustin AS: Role of MAP kinase signaling pathways in RSK2 activation in vascular smooth muscle cells. Biochemistry and Molecular Biology'99 (ASBMB Meeting), San Francisco. Faseb Journal 13 : A1489, 1999
- Mathews ST, Srinivas PR, Cintron VJ, Leon MA, Goustin AS, Grunberger G: a2-HS glycoprotein (human fetuin), a specific and reversible inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. 58th Scientific Sessions of the American Diabetes Association, Chicago. Diabetes 47 (Suppl.1) A442, 1998
- Grunberger G, Mathews ST, Srinivas PR: a2-HS glycoprotein inhibits trypsin-activated insulin receptor tyrosine kinase activity. 16th International Diabetes Federation Congress, Helsinki, Finland. Diabetologia 40 (Suppl.1) A141, 1997.
- Mathews ST, Srinivas PR, Goustin AS, Grunberger G: a2-HSG inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor and IRS-1 in vivo. 56th Scientific Sessions, American Diabetes Association, San Francisco. Diabetes 45 (Suppl.2), 116A, 1996.
- Mathews ST, Srinivas PR, Leon MA, Grunberger G: Bovine fetuin is an inhibitor of insulin receptor tyrosine kinase. ASBMB/ASIP/AAI Joint Meeting, New Orleans. Faseb Journal 10(6), A1247, 1996.
- Grunberger G, Srinivas PR, Mathews ST, Leon MA, Goustin AS: a2-HS glycoprotein inhibits insulin-stimulated insulin receptor signaling in vitro and in vivo. VI International Symposium on Insulin Receptors & Insulin Action - Molecular and Clinical Aspects, Copenhagen. Endocrinology and Diabetes 104 (Suppl. 2), 136-138, 1996.
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