Kristen Hertwig

Kristen graduated in December 2002 with a B.S. in Biochemistry.  She is currently employed with Amgen in San Diego, CA.  Kris joined the lab in January 2000, and contributed to several projects during her time in the laboratory.  Her work was divided into two main categories:  1) characterization of a novel extracellular catalase-peroxidase from E. coli O157:H7,  and 2) kinetic evaluation of peroxidase-catalyzed oxidation of capsaicinoids.  Her efforts in both these areas were fruitful.  She had the  opportunity to present her work at a number of meetings (see below), and papers have been published on both of her projects.  Kristen was selected to participate in the "Posters on the Hill" forum on Capitol Hill in Washington, D.C.  The event was sponsored by the Council for Undergraduate Research, and is designed to highlight the value of undergraduate involvment in research activities to members of the U.S. Senate and the U.S. House of Representatives (see some photos).  Kristen received awards for her participation in research including the Cell and Molecular Biosciences Undergraduate Summer Research Fellowship, and the Auburn University Undergraduate Research Fellowship.

Abstracts and Publications

Goodwin, D. C., Laband, K. A., and Hertwig, K. M.  2005.  Oxidation of capsaicinoids by peroxidases: kinetic, structural, and physiological considerations.  In  Phenolics in Foods and Natural Health Products.   Shahidi, F., and Ho, C. T., Eds. ACS Symposium Series, Vol. 909, pp. 161 - 174.

Varnado, C. L., Hertwig, K. M., Thomas, R., Roberts, J. K., and Goodwin, D. C. 2004.  Properties of a novel periplasmic catalase-peroxidase from Escherichia coli O157:H7.  Arch. Biochem. Biophys. 421, 166 -174.

Goodwin, D. C., and Hertwig, K. M.  2003. Peroxidase-catalyzed oxidation of capsaicinoids: steady-state and transient-state kinetic studies.  Arch. Biochem. Biophys. 417, 18 - 26.

Varnado, C. L., Hertwig, K. M., Thomas, R., Roberts, J. K., and Goodwin, D. C.  2003.  Characterization of a novel periplasmic catalase-peroxidase.  Amer. Chem. Soc. Southeast Regional Meeting, Atlanta, GA.

Varnado, C. L., Hertwig, K. M., Thomas, R., Roberts, J. K., and Goodwin, D. C.  2003.  Spectral and kinetic properties of a novel periplasmic catalase-peroxidase.  Amer. Chem. Soc. 226th National Meeting, New York, NY.

Goodwin, D. C., and Hertwig, K. M.  2003.  Transient- and steady-state kinetics of peroxidase-catalyzed capsaicinoid oxidation.  Amer. Chem. Soc. 226th National Meeting, New York, NY.

Hertwig, K. M., and Goodwin, D. C.  2002.  Characterization of a novel, extracellular catalase-peroxidase from E. coli O157:H7.  Council on Undergraduate Research, “Posters on the Hill” Forum, Washington, D.C.

Hertwig, K. M. and Goodwin, D. C.  2001  Cloning, overexpression, purification, and characterization of catalase/peroxidase from enterohemorrhagic E. coli O157:H7.  Amer. Chem. Soc. Southeast Regional Meeting , Savannah, GA.

Hertwig, K. and Goodwin, D.C.  2001.  Cloning, overexpression, purification, and characterization of catalase/peroxidase from enterohemorrhagic E. coli O157:H7. Amer. Chem. Soc. 222nd National Meeting, Chicago, IL.