2012 COSAM Distinguished Alumnus: F. Ivy Carroll

F. Ivy CarrollF. Ivy Carroll, chemistry ’57, was named the 2012 COSAM Distinguished Alumnus. Carroll is the distinguished fellow for medicinal chemistry for the Research Triangle Institute, or RTI, and is internationally recognized for his work as an organic and medicinal chemist. He was awarded a doctorate in chemistry by the University of North Carolina at Chapel Hill in 1961. He joined the research staff of RTI as a research chemist in 1960 and rose steadily to the position of vice president of the Chemistry and Life Sciences Group, a position he held from 1996 to 2001. Additionally, from 1975 to 2007, Carroll served as the director of RTI’s Center for Organic and Medicinal Chemistry.

With more than 50 years of scientific leadership and accomplishment at RTI, Carroll has made significant scientific contributions in the realm of drug discovery and development in areas such as anti-cancer, anti-radiation, and anti-malarial research. Among his most recognized work is the development of a diagnostic agent for Parkinson’s disease. He is also widely acknowledged for producing innovative compounds for potential treatments of cocaine and nicotine addictions and other central nervous system disorders. Carroll’s research is documented in 463 peer-reviewed publications, 33 book chapters, and 45 patents. Additionally, he has trained more than 100 postdoctoral fellows.

He is a member of several prominent scientific organizations including the American Chemical Society, or ACS; is a fellow of the American Association for the Advancement of Science; a fellow of the American Association of Pharmaceutical Science; a fellow of the College on Problems of Drug Dependence; and a fellow of the Royal Society of Chemistry. Other professional and scientific activities include service on the Long-Range Planning Committee of the Medicinal Chemistry Section of ACS, and two terms of service on the ACS Offices and Awards Committee, including serving one term as chairman. Carroll has also served on the National Institutes of Health Molecular Neuropharmacology and Signaling Study Section; the Biochemistry Study Section of the National Institute on Drug Abuse Review Committee; the Molecular, Cellular, and Chemical Neurobiology Research Review Committee; and the Medications Development Division Review Committee of the National Institute on Drug Abuse, as chairman. Carroll has served on the advisory boards of several scientific journals, including from 1995 to 1999 on the Editorial Advisory Board for the Journal of Medicinal Chemistry. He has received numerous awards for his research accomplishments, such as the 1993 Pacesetter Award, National Institute on Drug Abuse; the 1993 Distinguished Speaker Award, North Carolina Section of ACS; the 2000 Southern Chemist Award, Memphis Section of ACS; the 2001 Charles H. Herty Medal, Georgia Section of ACS; the 2001 Margaret E. Knox Excellence Award, RTI; the 2002 Division of Medicinal Chemistry Award, ACS; the 2006 Nathan B. Eddy Award from CPDD; the 2006 Research Achievement Award in Drug Design and Discovery from AAPS; the 2010 North Carolina Award for Science; the 2010 National Institute on Drug Abuse Public Service Award for Significant Achievement; the GlaxoSmithKline 2012 Alfred Burger Award in Medicinal Chemistry from ACS; and the 2012 International Narcotics Research Conference Founder’s Lecturer Award.

In 2007, he was inducted into the ACS Medicinal Chemistry Hall of Fame.

- Photo courtesy of Ivy Carroll.