This is Research: Drug Safety in the Spotlight

Dr. Richard Hanson presents at the This is Auburn Faculty Research Symposium.

October 7, 2015

By Samantha Taylor

AUBURN UNIVERSITY, Ala. – Drug Safety was a topic of discussion last week as Dr. Richard Hansen, Department Head of Health Outcomes Research and Policy, spoke as part of the This Is Research: Faculty Symposia at the Auburn Hotel and Dixon Conference Center.

Hansen spoke at the symposia’s “Auburn Talks,” session, giving his presentation entitled “Advancing the Science of Drug Safety.” His presentation focused on finding methods to detect the risks of drugs and take them off the market as soon as possible.

Currently, drug safety research is influenced by tragedies that have driven policy to where it is today. It is often too expensive to detect rare events that may affect one in a thousand people. Hansen explained that there are ways to use population data to quickly and effectively take a drug off the market.

“With traditional mechanisms, everyone figures the problem out and a drug comes off the market,” Hansen said. “But, could we figure it out sooner and could we prevent the next thousand people from getting that drug?”

With new technology, the use of computer algorithms and machine learning can be beneficial to identifying risks. This can be implemented to look at patterns and data of past drugs and be refined to do a better job of predicting when a potential tragedy could happen.

HSOP also had several other faculty present posters at the symposium as part of the program’s poster presentations.

Rajesh Amin from the Drug Discovery and Development Department presented his poster entitled, “Novel PPAR-gamma Agonist Improve Diabetes Mediated Memory Impairment.” Serving as co-authors to the poster were Vishnu Suppiramaniam, Robert Arnold, and Orlando Acevedo (COSAM-Chemistry).

Richard Hansen from the Department of Health Outcomes Research and Policy also presented his poster entitled, “Antidepressant Medication Use and its Association with Cardiovascular Disease.”

Kim Garza from the Department of Health Outcomes Research and Policy presented her poster entitled “Effectiveness of Different Financial Incentives to Improve Medication Adherence.” Serving as co-authors were Richard Hansen, Kimberly Braxton Lloyd, grad student Justin Owensby, and P4 student Elizabeth Wood.

David Riese from the Department of Drug Discovery and Development presented his poster entitled, “Validation of a High-throughput Screening Strategy for Potential Targeted Melanoma Therapeutics.”

Jianzhong Shen from the Department of Drug Discovery and Development presented his poster entitled, “Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and Negative Regulator.”

Vishnu Suppiramaniam from the Department of Drug Discovery and Development presented his poster entitled, “Elucidation of Molecular Mechanisms of Chemobrain: Identification of Targets and Therapies.”



Drs. Raj Amin and Rusty arnold with their poster entitled “Novel PPAR-gamma Agonist Improve Diabetes Mediated Memory Impairment.”

Dr. Richard Hanson with his poster entitled “Antidepressant Medication Use and its Association with Cardiovascular Disease.”


Dr. Kim Garza with her poster entitled “Effectiveness of Different Financial Incentives to Improve Medication Adherence.”

Dr. David Riese with his poster entitled “Validation of a High-throughput Screening Strategy for Potential Targeted Melanoma Therapeutics.”


Dr. Jianzhong Shen with his poster entitled “Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and Negative Regulator.”

Dr. Vishnu Suppiramaniam with his poster entitled “Elucidation of Molecular Mechanisms of Chemobrain: Identification of Targets and Therapies.”

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About the Harrison School of Pharmacy
Auburn University’s Harrison School of Pharmacy is ranked among the top 20 percent of all pharmacy schools in the United States, according to U.S. News & World Report. Fully accredited by the Accreditation Council for Pharmacy Education (ACPE), the School offers doctoral degrees in pharmacy (Pharm.D.) and pharmaceutical sciences (Ph.D.) while also offering a master’s in pharmaceutical sciences. In 2014, the school adopted the slogan, “Making Medications Work Through Innovative Research, Education and Patient Care.” For more information about the School, please call 334.844.8348 or visit http://pharmacy.auburn.edu.

Last Updated: October 7, 2015