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DMS Statistics Seminar
Time: Nov 10, 2017 (11:00 AM)
Location: Parker Hall 246

Speaker: Liang Liu, Associate Professor, Department of Statistics, University of Georgia

Title: An age-dependent birth-death model for gene family evolution

Abstract: In this study, we describe a generalized birth-death process for modeling the evolution of gene families. Use of mechanistic models in a phylogenetic framework requires an age-dependent birth-death process. Starting with a single population corresponding to the lineage of a phylogenetic tree and with an assumption of a clock that starts ticking for each duplicate at its birth, an age-dependent birth-death process is developed by extending the results from the time-dependent birth-death process. The implementation of such models in a full phylogenetic framework is expected to enable large scale probabilistic analysis of duplicates in comparative genomic studies.

Last updated: 11/07/2017