Endocrinology II

Growth Hormone
  1. Introduction (See Figure 1)
  2. Metabolic Effects
    1. Protein Metabolism
      1. Amino acid transport
      2. Ribosomal activity
      3. mRNA synthesis
    2. Lipid Metabolism
      1. Lipolysis
      2. Beta oxidation
    3. Carbohydrate Metabolism
      1. Decreases cellular uptake
      2. Diabetogenic Effect
  3. III. Growth Hormone and Growth
    1. Factors effecting growth
    2. Ossification
      1. Intramembranous
      2. Endochondral
    3. Role of Somatomedins (IGF's)
      1. Examples
      2. Problems & Challenges
  4. Regulation
    1. GHRH & GHIH (Somatostatin)
    2. Factors
      1. Low glucose
      2. Low fatty acids
      3. High protein
      4. Sleep
      5. Stress
      6. Exercise
    3. Feedback
    4. Complexities
  5. Pathologies
    1. Dwarfism
    2. Giantism
    3. Acromegaly
  6. Speculation
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