I.        Introduction
            A. Types and Classification
            B. Skeletal muscle properties
            C. Concept of motor unit

II.      The Neuromuscular Junction
            A. Anatomy
            B. Physiology

III.     The Muscle Fiber
              A. Introduction
              B. Myofibils, Filaments, Actin & Myosin, Titan, (Figure 1) 
              C. Membranous Systems
                      1) Sarcoplasmic reticulum

                      2) T-tubular System (see Figure 3)

                      3) Functions
 

IV.     The Thick Filament
             A. Structure (Figure 4) 
             B. Characteristics

 V.      The Thin Filament
            A. Structure
            B. Relationship between Actin & Myosin filament

VI.      The Physiology of Contraction - Ratchett Theory

VII.     Regulation of Contraction
             A. Regulation by Troponin & Tropomyosin
             B. Regulation by Calcium
             C. Regulation by ATP

VIII.    Energy Sources - ATP
             A. Creative Phosphate
             B. Oxidative Phosphorylation
             C. Glycolysis

IX.      Skeletal Fiber Types & Characteristics
              A. Type I
              B.  Type II a
              C.  Type II b

 X.      Form Curves - The simple twitch

XI.       Smoothing and grading
            A. Multiunit or multiple motor summation
            B. Wave Summation
            C. Asynchronous Firing
            D. Starling Principle

XII.      Smooth Muscle
            A. Structure
            B. Organization
            C. Physiology (Actin-linked regulation vs. Myosin-linked regulation)

XIII.     Pathologies
            A. Muscular Dystrophy
            B. Functional Dytonias
            C. Myasthenia gravis

XIV.     Pharmacology
            A. Nuromacular Junction
                 1.Stimulators (Acetylcholine Esterase Inhibitors)
                    a. physostigmina (ESERINE)
                    b. (PROSIGMIN)
                    c. organophosphates
                 2.Inhibitors
                    a. curare
                    b. succinylcholine
                    c. botulin (BOTOX)
            B.  Muscle Relaxants
                    (FLEXERIL)
                    (SKELAXIN) (SOMA)