Record: Normal ECG and Arterial Blood Pressure

    Discussion:     Explain the terms "systolic" and "diastolic"; also, how blood pressure is related
                          to heart rate, stroke volume, and peripheral resistance. Discuss the major
                          neurocirculatory reflexes important in the short-term regulation of blood
                          pressure. Give data from record.

Section B -
 
    Records:  1)    Effect of ACh
                    2)    Effect of Atropine followed by ACh

    Discussion:     Mention the types and loci of cholinergic receptors associated with the
                          circulatory system and how each responds to exogenous ACh to bring about
                          the expected changes in heart rate and blood pressure. Describe the action
                          of atropine, and tell which of the previously mentioned receptors are affected.
                          Explain which cholinergic receptors can still respond to exogenous ACh in the
                          atropinized animal to affect blood pressure. Support with data from record.

Section C -
 
    Record: Effect of Epinephrine

    Discussion:     Discuss the adrenergic receptors (location and type) which may influence
                          heart rate or blood pressure, and how each affected the observed response to
                          infusion of epinephrine. Support with data from record.

Section D -

    Record:    1)    Effect of clamping below the Carotid Sinus
                    2)    Effect of Medullary Ischemia

    Discussions:         1)    Carotid sinus reflex - completely discuss the physiology of this
                                       reflex, naming the nerves involved in the afferent portion, and
                                       the areas of the CNS which are involved. How does
                                       constricting the carotid bring about the expected change in
                                       systemic blood pressure? Support with data from record.

                               2)    Response to Medullary Ischemia - Describe the CNS area
                                       involved and the changes in blood supply and blood content
                                       which trigger the expected response. How is the expected
                                       change in blood pressure brought about? Give data from record.